[alevskaya]

The static shape of a protein doesn't automatically give you a prediction of its functional properties. There's a hell of a lot more biophysics going on that we have no predictive models for that are needed to understand catalysis, allostery, assembly, etc etc etc. We don't even have good comprehensive data for any of that (compared to sequences or structure) to model with.

Fold prediction is an incredibly useful tool for scientists and genetic engineers to help design new proteins, but it doesn't magically solve molecular or cell biology. Designing new functions and mechanisms is still going to involve a huge amount of labor and brute-force experimentation.