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anatnom | 2 years ago

For more comprehensive history/theory of Varespladib for snakebites, check out "Varespladib in the Treatment of Snakebite Envenoming: Development History and Preclinical Evidence Supporting Advancement to Clinical Trials in Patients Bitten by Venomous Snakes" (2022)[0] by the same Dr. Lewin this article is about. There's some interesting discussion of prior research in pigs where oral Varespladib is lifesaving for much longer time spans than injected antivenom, and a ton of somewhat-comprehensible cited sources.

[0] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9695340/

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