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CitizenKane | 2 years ago

I'm autistic and while it's nice to see ongoing research, I can't help but feel like this misses the point somewhat.

In particular I've seen a number of studies that make the jump from Fragile X syndrome to autism which I think is ill advised to say the least. There are a large number of genes[1] that are related to autistic individuals, and it's a very heterogeneous condition. In particular many, perhaps even most autistic individuals don't suffer from intellectual disability, don't have any physical characteristics which would set them apart from others, and don't tend to have problems with memory. All of these are characteristics of Fragile X syndrome.

> “Imagine being at a party, talking to a friend while music is playing in the background,” Frick says. “You have to integrate the sound of their voice with the movement of their lips.” But if there’s variability in sensory processing, socializing will be more challenging, he says.

And I'll take issue with this in particular. Frankly, the social issues of autistic individuals are wildly overstated and can be easily explained. Believe me, I know quite a few autistic folks and none of them have issues understanding when someone is speaking, we can tell. However, trying to sync up different minds that operate in different ways is a difficult problem.

Even among men and women with the same neurotype there's enough difference to cause _substantial_ misunderstandings. Enough ink has been spilled on the topic of relations between the sexes to fill oceans. And the difference between neurotypes is far more substantial than the difference between sexes in this regard. It's very easy for me to socialize with other autistic folks, I've had many conversations that have lasted hours on end. Doing the same thing with someone who is neurotypical though is much more difficult, and usually requires a willingness to put up with the awkwardness of not having the same vibe.

Finally, I won't go into anything about using mouse models for complex neurological conditions at the moment. But suffice to say, this article would be more properly titled "Noisy brain may underlie some of Fragile X syndrome's sensory features", but that probably doesn't get the same amount of attention.

[1] https://gene.sfari.org/

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satokema|2 years ago

> none of them have issues understanding when someone is speaking

This isn't it at all. It's the first part that's the issue. It's not that I can't understand speech, it's I can't focus on having a conversation increasingly as the number of chaotic elements increase.

There's loud(ish) background noise, there's people moving around, there's the uncomfortable feeling of strangers nearer to me than I would optimally like. And so I've realized in my younger attempts to fit in that I couldn't relax and have a good time and talk to people because of some of those things, because they felt to me like immediate urgent things and the conversation while I would like to have it is not getting priority.

A similar thing happens in larger group contexts, more people is more mental overhead, and additionally there's an element of not knowing how to take a turn in group conversation because I either lack an appropriate referent to relate or I don't know when my turn is.

By the time I have both something to say and can pay attention to turn taking the conversation has already moved on and I have to start over.

But neurotype is definitely a strong element in it, both in interests and somehow in things like conversational turn-taking as well. It also helps that a lot of conversations end up happening in text for me, turn-taking isn't an issue when you can both type at the same time.

Anotheroneagain|2 years ago

What they actually mean is that the music is so loud that it's PHYSICALLY impossible to hear, and "neurotypical" people are making up what other people say.