[ptoo]

I'm leaning towards there being no causation between skin microbiome and wrinkles.

Did anyone in the study have botox? Crow's feet wrinkles are generally caused by two things: UV damage, and movement of facial muscles breaking down collagen. Which naturally tend to increase with age. So that's where I'd wager the causation is.

If a person uses factor 50 every day on their face and gets biyearly botox injections on their crow's feet area, they'll likely have no prominent wrinkles but they will still be old and with a greater skin microbiome.

[m463]

I thought smoking had a pronounced effect on skin aging.