[moh_maya]

In mice;

and there are some anatomical differences between mice and humans..

So its open at this point whether it is relevant directly to humans.

IIRC, mice do not get Alzheimer’s, for instance. There are mouse models (genetically engineered)that exhibit some of the physiological symptoms of Alzheimer’s; but mice make particularly poor models for human neurology [1]- so this reach for using these essentially biomechanical structures to identify parallels and try to target a cure for neuro-degerative disorders in humans: seems more like a grant application attempt. I do wish press releases were a little more circumspect about such claims.

[1] https://www.statnews.com/2019/04/16/trouble-mice-behavioral-...

[NeuroCoder]

They do say they plan to verify findings in primates as well so perhaps the accomplishment here is more concerning the methodology. So there me be some greater merit to this work going forward.

I think it would be more interesting for this kind of study to verify these measures that can only be obtained in animals with neuroimaging. There have been some interesting attempts to move monitor aspects of CSF flow through MRI but we need to make sure we are measuring what we think we are before using in the clinic