> Proteins (for example Glial Fibrillary acidic protein, GFAP) had previously been identified as potential biomarkers for dementia in smaller studies, but this new research was much larger and conducted over several years.
The article (University press release) does mention this... but seeing a known suspect in the biomarker list would lend some confidence to any novel biomarkers found. So, it's good to see multiple studies having similar hits.
Totally a good thing. There's a very long list of biomarker failures, and there's lots of analysis into why so many biomarkers fail in clinical applications.
They mention this in the article, and of course, the scientific method means we _want_ to have more than one suggestive meta-analysis before we declare any kind of "discovery" at all.
> Proteins (for example Glial Fibrillary acidic protein, GFAP) had previously been identified as potential biomarkers for dementia in smaller studies, but this new research was much larger and conducted over several years.
mbreese|2 years ago
The article (University press release) does mention this... but seeing a known suspect in the biomarker list would lend some confidence to any novel biomarkers found. So, it's good to see multiple studies having similar hits.
buyohmarkers|2 years ago
One starting point for reading: https://academic.oup.com/clinchem/article/59/1/202/5622131
rablackburn|2 years ago
> Proteins (for example Glial Fibrillary acidic protein, GFAP) had previously been identified as potential biomarkers for dementia in smaller studies, but this new research was much larger and conducted over several years.