[t_serpico]

https://onlinelibrary.wiley.com/doi/10.1002/bies.201300153 tl;dr: metabolism is all you need.

while potentially interesting work, very shortsighted and premature to say this is a "GPT" moment in biology. ML people in bio need to think hard not only about what they are doing, but why are they are doing it (other than this is cool and will lead to a nice Nature publication). Their basic premise (learning from DNA is the next grand challenge in biology) is shaky. Imo, the grand challenge in biology is determining what the grand challenge is, and that is a deep scientific/philosophical question.