I’m surprised this article wasn’t about Metformin, something gwern has written about[0] and has some popularity in the entire nootropic circle of people that I know.
Metformin has been under scrutiny in recent years, several big studies failed to reproduce, and I'm pretty sure the consensus right now is that it's ineffective. NAD precursors are going through the same thing right now as far as I know.
"probably also offers only a constant reduction in risk without decreasing the acceleration of risk, if for no other reason than hundreds of millions of people have taken metformin over the past century yet no gerontologist has ever noticed a massive overrepresentation of diabetics among centenarians"
Ummm, and also WW2 planes that made it back to the base had damage in the least crucial areas.
slily|1 year ago
riehwvfbk|1 year ago
"probably also offers only a constant reduction in risk without decreasing the acceleration of risk, if for no other reason than hundreds of millions of people have taken metformin over the past century yet no gerontologist has ever noticed a massive overrepresentation of diabetics among centenarians"
Ummm, and also WW2 planes that made it back to the base had damage in the least crucial areas.
unclenoriega|1 year ago