[pdm55]

Of course, the study of how living cells function is "hard". But that doesn't mean it has to be learnt without joy. We tend to explore things we enjoy. A lot of the writer's essays [1] are about finding some aspect of a topic intriguing and following that rabbit hole.

My own research centered on one subset of functions within E. coli. I was lucky that I found a carefully engineered subset of plasmids and adaptions of E.coli, that could be mathematically modelled [2] [3]. I didn't have to know the whole functioning of E. coli. I didn't have to use mathematics beyond algebra. That is, no calculus was needed. The key task was to put together the quantitative research of about half a dozen labs. Okay, I had a "mountain" of articles to read. And it took 5 years of effort. But it was only doable, because I was modelling a carefully constrained subset of cellular functions.

[1] https://jsomers.net/

[2] https://pubmed.ncbi.nlm.nih.gov/8078069/

[3] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5425810/