[cam-o-man]

No, and there is a (piloted) drone attack in the first book -- Paul is attacked by a hunter-seeker.

The reason nobody tries to use the lasgun-shield interaction as a weapon is because the resulting explosion is indistinguishable from a nuclear weapon, and the Great Convention prohibits the use of nukes on human targets.

Just the perception of having used a nuclear device would result in the House which did so becoming public enemy #1 and being eradicated by the Landsraad and Sardaukar combined.

[archi42]

Nope. That's all I'm going to spoiler;-)

@Potro: If you liked the movie, read the books. I don't read a lot anymore, but during sick leave I started with the first book. Didn't stop until I finished the main story, including the sequels by Frank Herbert's son about a month later. That's like... uh... nine books?