[p3opl3]

Yes, because that's going to stop competitors.. it's why they didn't release code I guess.

This is yet another large part of a biotech related Gutenberg moment.

[natechols]

The DeepMind team was essentially forced to publish and release an earlier iteration of AlphaFold after the Rosetta team effectively duplicated their work and published a paper about it in Science. Meanwhile, the Rosetta team just published a similar work about co-folding ligands and proteins in Science a few weeks ago. These are hardly the only teams working in this space - I would expect progress to be very fast in the next few years.

[dekhn]

How much has changed- I talked with David Baker at CASP around 2003 and he said at the time, while Rosetta was the best modeller, every time they updated its models with newly determined structures, its predictions got worse :)