It is being used off label all over the place for heart conditions. That’s why i take it. The on label use is actually pretty annoying for the first few months.
Long term PDE 5 treatment lowers estrogen and increases testosterone. As a consequence of that, and its cardiovasvular effects, it makes it easier for the body to turn fat into energy by fat-browning, to grow muscles and to lose fat.
Tadalafil works well for getting more out of your workouts too (I take that). Gives you an overall feeling of well-being too (better than any cup of joe), I no-bullshit begin my day with it.
I know a former executive of the company that was developing this drug for cardiovascular problems. He told me that they sold it because it had this "side-effect" that they couldn't get rid of. ;-)
Marketing is the key to business success.
(Talking to you, tech people)
We don't know how many medications actually function. We put them inside of increasingly complex animals and study the results to see what they do (and hope they don't die). Botox was intended to treat muscle spasms. Powerful anti-depressants are regularly prescribed for pain from nerve damage in people with no mental health issues. And MDMA isn't prescribed for anything because the powers that be prematurely decided to ban it based on completely fabricated claims, which I assume is part of a massive hundred-year conspiracy to make sure people... keep dying from alcohol? Not totally sure about that last one, but it's hard to deny the facts.
I work on health equity things in healthcare occasionally. I think this is so dumb. MDMA rejected by panel recently for evaluating rescheduling for use in PTSD.
“ Panelists pointed to flawed studies that could have skewed the results, missing follow-up data on patient outcomes and a lack of diversity among participants. The vast majority of patients were white, with only five Black patients receiving MDMA, raising questions about the generalizability of the results.
“The fact that this study has so many white participants is problematic because I don’t want something to roll out that only helps this one group,” said Elizabeth Joniak-Grant, the group’s patient representative. “
this is the case with almost all drugs. for example almost every antidepressants was the result of a weight loss or something like that.
drug research is worse than training an LLM. you feed it to random people and then compare effects with initial conditions and of something looks good you try with more control.
paiute|1 year ago
newswasboring|1 year ago
jbandela1|1 year ago
However, it seems that there was at least theoretical consideration that it could be used to treat ED
A nice overview is here:
https://www.nature.com/articles/nrd2030
mikercampbell|1 year ago
Traubenfuchs|1 year ago
salad-tycoon|1 year ago
brandall10|1 year ago
hammyhavoc|1 year ago
lebuffon|1 year ago
Marketing is the key to business success. (Talking to you, tech people)
grogenaut|1 year ago
Phoenix5869|1 year ago
standardUser|1 year ago
salad-tycoon|1 year ago
“ Panelists pointed to flawed studies that could have skewed the results, missing follow-up data on patient outcomes and a lack of diversity among participants. The vast majority of patients were white, with only five Black patients receiving MDMA, raising questions about the generalizability of the results.
“The fact that this study has so many white participants is problematic because I don’t want something to roll out that only helps this one group,” said Elizabeth Joniak-Grant, the group’s patient representative. “
Hopefully the VA can lead the way.
https://apnews.com/article/mdma-psychedelics-fda-ptsd-ecstas...
1oooqooq|1 year ago
drug research is worse than training an LLM. you feed it to random people and then compare effects with initial conditions and of something looks good you try with more control.
ekianjo|1 year ago
caycep|1 year ago