top | item 40657680

(no title)

spacetimeuser5 | 1 year ago

All the empirical examples you mentioned pertain to the extracellullar space. So is this stochastic modelling also true in the intracellular space, which is like 100x times denser structurally, biochemically and bioelectrically (given that all biochemistry is effectively a type of electrical process involving very refined transfer/manipulations of charge densities), and allows to explain how do hundreds or thousands of biochemical reaction inside cells happen as required without interfering with each other?

Evolution also "tries" to save energy anywhere possible, so spending energy on the synthesis of endogenous ligands, which eventually will be discarded, seems a bit redundant. There is also a theorem in evolutionary game theory, that probability that natural selection will allow an organism to see reality as it is (=the truth) is exactly zero, as it's enough to make it just "good enough". I was arguing about that with Gemini, and it agreed with me. My point is that "evolution" is just a tool (like ChatGPT) with it's own instrumentally limited pool of empirical data (80% of which was also obtained from macroscopic enough observations rather than reverse engineering or experimentation) to build upon.

I actually want to apply one EE concept, which has some experimental basis. The reason why I am digging this, is that I am searching for some possible explanations of a couple of dozens of experimental studies in bioelectrics/magnetics I found. (though won't discuss in depth on a public forum)

discuss

order

Balgair|1 year ago

I mean, how is the intracellular space denser than the extracellular? That means they wouldn't float.

The stochastic nature of the cell, as far as I know, exists pretty much the same in and out. With more transport mechanims occurring inside to make sure things get to where they need to be.

It's not that the discarded ligands (for example) are really 'discarded'. There are a few instances I know of that use the 'waste' as a product unto themselves. The ToR network comes to mind here. Still, trying to really figure out what the 'intention' was all those billions of years ago is hard, and networks and feedback loops have been built up over the eons. Like, yeah, nothing is really wasted in a cell, per se. But it can seem that way in the chain that you're looking at.

I'd love to know more about the magnetic side of things here. Is it memristors as synapses? Because that is a criminally misunderstood area of neuroscience.

spacetimeuser5|1 year ago

>>how is the intracellular space denser than the extracellular?

Gemini: ``` Yes, the intracellular space is denser than the extracellular space:

Here's why:

    Packing: Cells are packed with molecules like proteins, carbohydrates, and nucleic acids. These molecules take up a significant amount of space within the cell, leaving little room for just water.
    Solutes: The intracellular space contains a higher concentration of dissolved molecules (solutes) compared to the extracellular space. This contributes to a higher density.
    Extracellular Matrix: The extracellular space, on the other hand, contains a looser network of connective tissues and fluids like interstitial fluid. This allows for more space between molecules, resulting in a lower density.
```

>>Still, trying to really figure out what the 'intention' was all those billions of years ago is hard

With this logic you'll need another billion of years to randomly figure it out. I'd rather focus on how/efficiently does such position contribute to a specific current experimental methodology or results.