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jawon | 1 year ago

"The team used mice that develop a form of Alzheimer's. They exposed these mice to bursts of sound and light that occurred 40 times a second.

The stimulation induced brain waves in the animals that occurred at the same, slow frequency.

Tests showed that the waves increased the flow of clean cerebrospinal fluid into the brain and the flow of dirty fluid out of the brain. They also showed that the fluid was carrying amyloid, the substance that builds up in the brains of Alzheimer's patients."

Does this mean we might be able to use something like TMS instead of sleeping?

And could a failure or reduced functioning in this system explain those people "allergic" to electromagnetic radiation?

discuss

order

tsol|1 year ago

Cleaning the brain is one function that is fulfilled during sleep, but it isn't the only function. Even if you can artificially induce this you would probably need to sleep for other things such as physical recovery(which intensifies during sleep). There may be a chance that it helps lessen the need for sleep or maybe even remove some of the deleterious effects of sleep deprivation

AuryGlenz|1 year ago

I volunteer to try it out. I have idiopathic hypersomnia and if I get even a few minutes short of what I’m supposed to it (seems to) hit me like when most people get a few hours short.

Seriously. Anyone in HN know how I could replicate this?

sandwitches|1 year ago

Here's a good rule of thumb: any time you try to undo a billion years of evolution, there will probably be unintended side effects. Go to bed.

euroderf|1 year ago

New daily/weekly schedule based on tracking animals to exhaustion:

1) Walk for a day or two, with naps during afternoon heat. 2) Eat absolutely enormous meal. 3) Sleeeep. 4) Repeat.

caeril|1 year ago

"Go to bed" is useless advice. Some of us are unable to sleep longer than about 5 hours. Room darkening, white noise, complete silence, 8Sleep mattress pad, extended release melatonin, caffeine abstinence, going to bed later, going to bed earlier, nothing works. We just naturally wake up after 5 hours, no matter what, ready to go.

SV_BubbleTime|1 year ago

Yea… um, also… I like sleeping. I find it a nice change of pace compared to the rest of my day.

ekianjo|1 year ago

mice models are notoriously known for being bad to predict anything related to the actual disease pathways

SV_BubbleTime|1 year ago

“Humanized mice”… yea, still mice though.

I’m kind of not joking that I think asking for medical study volunteers from prison populations in exchange for time served would put us way ahead.

Or instead of the death penalty, we try some things out that maybe might not work.

We would have cured for colds, cancers, and hair loss in a few years of human testing.

spacetimeuser5|1 year ago

If 40 times a second is 40 Hz, than this frequency is pretty high for a deep sleep (in humans), 40Hz would mean some intense pattern recognition/focused attention.

BigParm|1 year ago

"Does this mean we might be able to use something like TMS instead of sleeping?"

The trillionaires will greatly benefit from our new 20 hour work days.

Grimblewald|1 year ago

Sleep is about more than waste removal. You cant really learn new things without sleeping on it.

XorNot|1 year ago

That's making an assumption that the two aren't actually entirely linked phenomena.