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stenl | 1 year ago

TERT activation is one of the most common alterations causing cancer. In fact, the whole point of the normally very low TERT expression in somatic cells is likely to be cancer prevention. It’s the mechanism behind the Hayflick limit, which puts a bound on the max number of divisions a cell can go through, via telomere shortening. Without such a limit, you get cancer. I highly doubt it will make you live longer.

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AstralStorm|1 year ago

Sure it likely will. However, it may also get you cancers, for which we'd need to enhance other cancer preventing mechanisms. TERT is essentially a fallback.

Plus perhaps you can have a "rejuvenation session" with TERT instead of boosting it forever. Thing seems like it can work after TAC is no longer being activated for quite some time.

Ultimately though yes, it may increase the number of cells that have already taken multiple hits if multiple hit cancer hypothesis is really true.

jb1991|1 year ago

Until there is a cure for cancer.