[bzalasky]

Make sure to eat food before you take it, and start with 2.5g twice a day instead of 5g all at once to go easy on your stomach. The food helps slow down how quickly the creatine moves through your system. This prevents too much water from being pulled into your GI tract, avoiding undesirable symptoms (use your imagination).

[worthless-trash]

As more anecdata, I eat it all times of the day and have no undesirable symptoms, before food, after food, while not eating at all, it simply doesn't have enough impact on the stomach for me to notice.

[bzalasky]

I get that it might treat people differently. This is what works for me, otherwise I wouldn’t be able to take it at all.