[jsmeaton]

Rye was started by Armin as a collection of existing tools (mostly) with a frontend similar to cargo.

Then Astral came out with uv which aims to be a frontend into a collection of their own tools similar to cargo.

Armin and Astral agreed for Astral to take over Rye some time during uv development with (I assume) the goal for uv to fully replace Rye.

Use uv. As of 0.3.0 it covers most of rye now anyway. Especially if you’re writing projects and not consumable libs/apps (I haven’t used uv for anything other than package management so far).