This is interesting work but I think something has been intentionally overlooked. Creating proteins is difficult and it's also unclear how many of these sequences folded into the predicted 3d structure. Small molecule synthesis is still easier, cheaper, and more scalable than protein therapeutics. I think this would've been more impactful had they focused on improving on the SOTA small molecule - protein interaction models.
flobosg|1 year ago
The whitepaper depicts some successful cases, determined by X-ray crystallography or cryo-EM.