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wpasc | 1 year ago

amen. I've tried 3 tnf inhibitors that have not worked (and had negative side effects). Cosentyx (il 17a inhibitor) kinda scares me. I always like to keep my hopes that some better autoimmune treatments could come soon

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throw241005|1 year ago

Out of curiosity I'm curious why it scares you?

For context, I had been on Taltz before for psoriasis, and it worked very well. It seems like il17 inhibitors specifically are extremely targeted in what they affect.

In comparison, I was also on otezla at one point (tnf-a inhibitor) and it didnt work for me either, and the side effects were terrible.

wpasc|1 year ago

It's the few instances of new onset IBD and generally the GI side effects. I'm lucky enough to have a pretty solid GI system that I don't want to risk messing with. I get very anxious with medicine, and my ankylosing spondylitis is sufficiently slow moving on MRI and tolerable enough that I prefer not to use the medicines. I had too many strange side effects whilst on Humira/Remicade such that it scares the crap out of me.

notheyarent|1 year ago

You had a skin fungal infection dumbass not some unknown mystery condition psoriasis they came up with