[throwaway041207]

> I am very cautious about the potential for damaging long-term side effects.

This is fair. But I'll ask you this: how long would it take for you to trust it? Assuming there are no side effects beyond what we know now, which are:

* gastroparesis is a small number of patients

* elevated thyroid cancer risk in mice

* nausea and general uncomfortableness when taking it (some percentage, not all)

* muscle and bone loss which seems to be roughly on par with any rapid weight loss approach

* a small percentage of people develop malaise, anhedonia and suicidal ideation

* a propensity to gain some percentage of weight back and/or relapse in addictive behavior when going off the drug

These are the side effects we know about with over a decade of prescribing GLP-1 agonists. Assuming these continue to be the primary side effects, how long would you wait until you are comfortable in trusting they are the only ones?