[riahi]

Strictly speaking, phenylphrine works when it’s injected. It is approved and used every day for this indication in the service of general anesthesia.

However, the oral bioavailability is zero.

This is an example of using something off label that’s approved for something else. Sometimes it’s fine. And sometimes, it’s dumb.

[gambiting]

That's cool to know - I had no idea! I assumed that it literally did nothing in every scenario.