[moh_maya]

From the article:

“Early human studies of ketogenic compounds have improved cognitive scores in patients with mild to moderate AD.”

While it requires behaviour changes (for the diet), this is something that's relatively easy to test & validate, and with a good sample size.

Edit: To elaborate -- getting on a keto diet results in production of ketone bodies; the keto diet is (IMO) hard to adhere to, but not impossible.

And if it is ketone bodies in the brain that are important, iirc, you can supplement the body with exogenous ketones (which the article alludes to, and the authors appear to be planning to test) which could potentially help.

If there's a measurable, significant effect with just consumption of exogenous ketones without even having to enter ketosis via diet- wow!

[delichon]

I'm all keto / very low carb for 4 plus years. I have been on dozens of different diets, not an exaggeration. Other than the eat whatever I want diet this has been by far the easiest for me to maintain long term. For me eating just a little bread is an insurmountable goal, but eating none I can do. I wouldn't have always traded carbs for a few extra years of cognitive function, but post addiction it feels like a good deal, if I can still get it.