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epmatsw | 1 year ago

Re: longevity, ITP didn't find any significant impact from metformin. Afaik they're the most rigorous testers of this sort of thing, so that's pretty significant to me.

https://pubmed.ncbi.nlm.nih.gov/27312235/

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ziddoap|1 year ago

>ITP

Interventions Testing Program (by The National Institute on Aging) for the unfamiliar, like me.

klipklop|1 year ago

...in mice.

Also.

>Metformin (0.1%) combined with rapamycin (14 ppm) robustly extended lifespan, suggestive of an added benefit, based on historical comparison with earlier studies of rapamycin given alone.