[thereticent]

You just described the exact end goal of my overall research program, if we can keep the stroke, AD, and Down syndrome + AD cohorts running. Associating blood biomarkers differentially with individual disease processes and comorbid health factors is the holy grail.

Perverse professional norms and plenty of miscreants have made it a much harder road for other dementia researchers, but it's worth keeping on, and there are so many avenues that haven't been pursued.