[WindyMiller]

...IN MICE

[mlhpdx]

And not just mice, but mice engineered with “T1D like” conditions. Human testing too early is certainly undesirable but these studies with mice, while necessary and important, are nothing newsworthy for the general public (but good for fundraising for follow up work).

[bitwize]

Late last year a woman's T1D was put into remission using beta cells derived from her own stem cells: https://www.nature.com/articles/s41591-024-03394-9

She was on immunosuppressants, so how long the new beta cells would last without those is still an open question. Other similar, ongoing trials are showing promising results.

[strkitten]

Indeed, I would appreciate if the title were updated to reflect that the subjects were mice, not humans. It’s a bit misleading.

[_carbyau_]

Yeah! How amazing is that! Reversing type 1 diabetes anywhere is amazing.

A way to go until it becomes an option for humans. And then way more to go until it becomes a preferred option.

But this is great news.

[jfengel]

Not if it requires immune suppressants. They can already transplant whole pancreases. They rarely do because the resulting lifetime of immune suppression is worse than the quite effective insulin injections.

Any research could pay big benefits eventually but this is far from "great news". It's a step forward along a path that is actually well behind the others.