[rnijveld]

I would argue compile time changes don't matter much, as the amount of data going through zlib all across the world is so large, that any performance gain should more than compensate any additional compilation time (and zlib-rs compiles in a couple of seconds anyway on my laptop).

As for dependencies: zlib, zlib-ng and zlib-rs all obviously need some access to OS APIs for filesystem access if compiled with that functionality. At least for zlib-rs: if you provide an allocator and don't need any of the file IO you can compile it without any dependencies (not even standard library or libc, just a couple of core types are needed). zlib-rs does have some testing dependencies though, but I think that is fair. All in: all of them use almost exactly the same external dependencies (i.e.: nothing aside from libc-like functionality).

zlib-rs is a bit bigger by default (around 400KB), with some of the Rust machinery. But if you change some of that (i.e. panic=abort), use a nightly compiler (unfortunately still needed for the right flags) and add the right flags both libraries are virtually the same size, with zlib at about 119KB and zlib-rs at about 118KB.