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RedditKon | 11 months ago

Phase 2 clinical trials showed 14.7% mean weight reduction at 36 weeks in adults.

That's pretty substantial. Obviously no one knows what Phase 3 will show, but cynicism seems unwarranted at this point.

https://investor.lilly.com/news-releases/news-release-detail...

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timewizard|11 months ago

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derektank|11 months ago

I don't understand what your criticism is here exactly. Of course Eli Lilly will release a press release if the results of a clinical trial are good but that doesn't make the underlying research (published in the Lancet [1]) suspect in any way. Clinical trials are overseen by the FDA and frequently conducted by third party research scientists without a financial stake in the long term success of the intervention being studied. In this case, it appears that the study authors were researchers at Velocity Clinical Research and they found significant body weight loss with side effects comparable with other GLP-1 agonists. Skepticism might be warranted, particularly until phase 3 trials are conducted, but mindless cynicism hardly seems warranted.

[1] https://www.thelancet.com/journals/lancet/article/PIIS0140-6...