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its_down_again | 10 months ago

The current title “How aging stem cells fuel visceral fat gain in middle age” suggests that existing stem cells simply ramp up fat production as they age.

Single-cell RNA sequencing of APCs then identified a new committed preadipocyte population that is age enriched (CP-A), both in mice and humans. CP-As displayed high proliferation and differentiation capacities, both in vitro and in vivo.

It should read more like "aging triggers emergence of a specific stem cell type (APCs) which drives visceral fat expansion"

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