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iamthemonster | 9 months ago

Which study are you referring to for keto having a negative impact on cardiovascular health? I've unfortunately found studies and metastudies reaching all sorts of conflicting conclusions on keto.

The top metastudies on a simple google search both conclude positive effects on CVD.

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Aurornis|9 months ago

Ketogenic diet research is fascinating in itself for how many manipulated or misleading studies get published.

The most recent example is the KETO-CTA paper, which was released in April to loud claims that high LDL in a keto diet was not really bad. It got picked up by various news outlets as vindicating ketogenic diets. The authors posted long Twitter threads full of meme animated gifs celebrating their victory over keto skeptics.

Yet when people started looming into the study they noticed that the study failed to report the data from the pre-registered trial endpoint. This is highly unusual because if you establish an entire clinical trial, you are expected to publish the primary results you pre-registered.

After a lot of prodding, people finally got the authors to release the percent change in non-calcified plaque volume (NCPV) values that they pre-registered for and they were extremely high. Even higher than seen in certain serious medical conditions. It became clear that they chose to hide the values because they were so incredibly bad.

> The top metastudies on a simple google search both conclude positive effects on CVD.

There are a lot of die-hard keto defenders who produce papers, blogs, and podcasts claiming it’s either neutral or good for CVD. You have to look past the SEO optimized content and go to actual CVD experts who do not have their internet presence tied to promoting keto diets.

iamthemonster|9 months ago

Thank you for your response. I've certainly found keto seems to inspire quite a tribal approach in many people - the r/keto subreddit has a certain dogma that is rigidly enforced, there's a pro-saturated-fat pro-meat tribe etc.

I initially gave keto a shot for two weeks, and I found unexpectedly high benefits in increased energy, weight loss and an end to some long-standing stomach ulcer issues. So my two-week trial has ended up lasting 3 months.

It's been frustrating that trying to learn about keto is like drinking from a firehose of bullshit, because I'm really rather enjoying my extra energy, weight loss and lack of stomach pain and ulcers. I actually feel 20 years younger.

I'm quite skeptical of the long term elimination of whole grains though, so soon I'll be easing off keto with some vegetables and whole grains.