[richarlidad]

Serious side effects from long term high dose vitamin B6 include peripheral neuropathy. Doses exceeding 500 to 1000 mg per day pose the greatest risk but prolonged intake of lower doses may also result in this side effect. The Therapeutic Goods Association of Australia has found that peripheral neuropathy can occur at doses of less than 50 mg.

In pregnant adult women, vitamin B6 is likely safe at a dose of up to 100 mg per day. In adolescent pregnancy, vitamin B6 is likely safe at a dose of up to 80 mg per day.

In lactating adult women, vitamin B6 is likely safe at a dose of up to 100 mg per day. In adolescents who are lactating, vitamin B6 is likely safe at a dose of up to 80 mg per day.

In children, vitamin B6 is likely safe at a daily dose of 30 mg (1-3 yrs), 40 mg (4-8 yrs), 60 mg (9-13 yrs) and 80 mg (14-18 yrs).

The likelihood of side effects increases at doses higher than 200 mg per day.

In 2023, the European Food Safety Authority set an upper limit of vitamin B6 of 12 mg per day for adults, and 2.2 to 10.7 mg per day for infants and children.

Source: https://inspectsupplement.com/vitamin-b6 (Edited Note: My Website)

[maqp]

Paywalled article.

Here's a good one https://ods.od.nih.gov/factsheets/VitaminB6-HealthProfession...

[richarlidad]

I've removed paywall.