[Solstinox]

I’ll let them go first. I insist.

We can barely manipulate simple organisms without causing negative second order effects to cascade through our systems.

[cjbgkagh]

It would be a matter of concentrating specific SNPs that are already identifiable in human populations. There is no need to create new SNPs of unknown outcomes. There would be no difference if the SNP was put there through intervention or if it was inherited by a parent. Since these SNPs already exist the outcomes can and are being studied.

[Solstinox]

These are the types of assumptions and blindspots that lead to unintended negative effects.

Your approach assumes that the distribution of those SNPs at the population level is immaterial.

What makes an allele attractive at one frequency can expose new liabilities at a different frequency.