[csl]

Yes, I can see how it would make sense to be able to set this in pyproject.toml (typically for private package)

uv is still quite new though. Perhaps you can open an issue and ask for that?

[collinmanderson]

It looks like there's already a pyproject.toml no-binary option?

   [tool.uv]
   no-binary = true

Or for a specific package:

    [tool.uv]
    no-binary-package = ["ruff"]

https://docs.astral.sh/uv/reference/settings/#no-binary