[Euphorbium]

I have not used 5-meo, but for n,n DMT the vape is without a doubt the most convenient method.

[gavinray]

I've done it a few times. Unlike DMT, you don't have to vaporize it.

It's active intranasally and well as buccally/sublingually.

Effects-wise, it feels roughly identical to DMT but with a longer duration.

[temp0826]

As someone who has done a lot of both (as well as drank ayahuasca several hundred times), they are completely different animals especially at the full-dose levels.

[fer]

I found it significantly less visual. As in, about as immersive, but somewhat lacking visual depth/detail to things. But everyone's different anyway.

[gehwartzen]

To me it feels like a completely different drug compared to nnDMT. 5-meo-DMT also feels very different depending on the roa from my experience (vaped vs IM)