Most interesting novel ideas originate at the intersection of multiple disciplines. Profitable trades could be found in the biomedicine sector when the knowledge of biomedicine and finance are combined. That's where I see LLMs shining because they span disciplines way more than any human can. Once we figure out a way to have them combine ideas (similar to how Gwern is suggesting), there will be, I suspect, a flood of novel and interesting ideas, inconceivable with humans.
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