The study mentions they administered 30 milligrams of psilocybin for 70 kg of body weight. Does anybody know how many grams of dried mushrooms that is equivalent to, roughly?
A good ballpark for dried shrooms is roughly 1% psilocybin by weight of dried shroom, so about 3g. That said, it's going to vary a lot shroom to shroom, genetic to genetics, and species to species. Could be as high as 6g for more mild strains and as low a 1g for something like pan cyans.
That is the problem with clandestine pharmacy by Florida man, as people may get the wrong dose or a mixture of various other poisons like arsenic (see dark web article.)
When ready, please talk with your doctor first. =3
"[...] psilocybin converts to psilocin in the body at roughly a 1:1 ratio by active effect [...]
Psilocybe cubensis (most common): Contains about 0.5-1.0% psilocybin by dry weight. Since psilocybin converts to psilocin in the body at roughly a 1:1 ratio by active effect, 30mg of psilocin would be equivalent to roughly 3-6 grams of dried P. cubensis.
Psilocybe semilanceata (liberty caps): Much more potent at 1-2% psilocybin content, so you'd need only about 1.5-3 grams dried.
Psilocybe azurescens: Even more potent at 1.5-2.5% psilocybin, requiring roughly 1-2 grams dried.
Important caveats:
- Individual mushrooms within the same species can vary by 3-5x in potency
Growing conditions, harvesting time, and drying/storage methods all affect potency
- The caps are typically more potent than stems
- Fresh vs. dried makes a huge difference (fresh mushrooms are ~90% water)"
Have to note that the paper is from 2016; for those really interested, it's good to read recent review papers.
awithrow|7 months ago
Joel_Mckay|7 months ago
When ready, please talk with your doctor first. =3
adamgordonbell|7 months ago
TrackerFF|7 months ago
EDIT: Never mind, didn't see that it was cubensis - which might take more due to being weaker than regular wild semilanceata.
locallost|7 months ago
scellus|7 months ago
"[...] psilocybin converts to psilocin in the body at roughly a 1:1 ratio by active effect [...]
Psilocybe cubensis (most common): Contains about 0.5-1.0% psilocybin by dry weight. Since psilocybin converts to psilocin in the body at roughly a 1:1 ratio by active effect, 30mg of psilocin would be equivalent to roughly 3-6 grams of dried P. cubensis.
Psilocybe semilanceata (liberty caps): Much more potent at 1-2% psilocybin content, so you'd need only about 1.5-3 grams dried.
Psilocybe azurescens: Even more potent at 1.5-2.5% psilocybin, requiring roughly 1-2 grams dried.
Important caveats:
- Individual mushrooms within the same species can vary by 3-5x in potency Growing conditions, harvesting time, and drying/storage methods all affect potency
- The caps are typically more potent than stems
- Fresh vs. dried makes a huge difference (fresh mushrooms are ~90% water)"
Have to note that the paper is from 2016; for those really interested, it's good to read recent review papers.
mock-possum|7 months ago