top | item 44769090

(no title)

voat | 7 months ago

Maybe not a drug. But if the improvements in health come from bio chemical signals, it should be possible to activate those signals without engaging in exercise. Eventually?

discuss

order

sctb|7 months ago

Strictly speaking, any intervention other than exercise is going to give you a subset of the total stimulation. A drug acting on the tissues directly would bypass the neurological component, for example.

If the idea is to avoid the effort of exercise, perhaps it would be worth considering the possibility that the effort itself is essential.

Bnjoroge|7 months ago

not entirely true. you can have drugs that directly act on the respective receptors, either inhibit or excite them.

vmg12|7 months ago

It would take a lot of different drugs to simulate what exercise does.

- Impact and stress strengthening the muscles, bones and tendons / ligaments

- energy use that leads to better sleep

- increased blood flow, development of new capillaries, stretching of blood vessels

- if you exercise outside, exposure to sunlight

- the release of all the associated neurochemicals

I have a suspicion that anything designed to mimic exercise would hurt as much as the actual thing given that so many of the benefits of exercise involve damaging bone and tissue then repairing it

tomalaci|7 months ago

Steroids. You will be growing muscle while sitting on a couch, even better than someone that naturally trains. However, you very likely will develop asymetries or other weird complications because you didnt properly work out.

My point is that, even though we might find even more ways to improve/modify our bodies, they will come with slew of risks that are just not worth it if you can achieve it naturally.

On another note, I feel like there is severe muscle inflation in media which would distort how fit a person should be. You really do not need to kill yourself in the gym or hop on a some reddit-approved juices to get very fit. Just gotta experiment and find a comfortable full body workout that you can do consistently, like you brush your teeth every day.

Fire-Dragon-DoL|7 months ago

You get plenty of asymmetries working out too, it's natural. Don't think just weight lifting, think of: tennis, boxing, baseball

samiv|7 months ago

Actually, that's not how steroids work. It's a common misconception that one can take "roids" and just sit on the sofa while munching on potato chips and get shredded and pack on muscle but in reality what the steroids do are to move ones natural limitations further away thus enabling larger muscle mass than naturally. But this still requires one to put in the work, i.e. the stimulus to trigger the muscle growth and to rest and eat properly.

deadbabe|7 months ago

That's not how steroids work. Muscles need stimulus to grow even with steroids. What steroids do is make your body recover faster so you can train more often and build muscle right away.

mythrwy|7 months ago

Yes we could also in potentially in the future manage to block pain signals when we stick our hand on hot stoves and that should be super!

socalgal2|7 months ago

The article has an opinion on this

> When I asked Ashley if it was possible to design a drug that mimicked the observed effects of exercise, he was emphatic that, no, this was not possible.

DaveZale|7 months ago

yes and no. A couple thousand myokines at work here.

Even lactate, formerly regarded as simply a waste product, is one.

But sure, a cocktail may be possible at some point, beyond getting a blood transfusion from someone fitter and maybe younger.

gonzo41|7 months ago

This is so bleak. Go for a walk.

toomuchtodo|7 months ago

Time is short, I’ll take the walk and lift the weights but if I can get the results faster using biological engineering, I’m willing to spend and accept greater risk to make it happen (both for metabolic profile management a la GLP-1RAs and muscle growth). There is no extra credit for making life harder than it has to be, and we’re all dead eventually.

Loughla|7 months ago

Why? My best friend uses a wheelchair and has dexterity issues in his hands due to a stroke.

Exercise for him is (a) expensive and (b) really really really painful.

If he could take a pill that simulated this it would be amazing for his life.