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frigidwalnut | 6 months ago

Follow up work has shown that result is a statistical artifact/does not replicate [1,2,3].

[1]https://academic.oup.com/genetics/article-abstract/229/1/iya...

[2]https://academic.oup.com/mbe/article/42/2/msaf041/8005733

[3]https://www.biorxiv.org/content/10.1101/2024.03.25.586640v1

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JumpCrisscross|6 months ago

Are there two proposed bottlenecks, one at 900 kya and another at 70 kya? I'd only really heard about the latter.

frigidwalnut|6 months ago

The paper linked in that post proposes a bottleneck at 900Kya in the ancestors of all modern humans. There is a bottleneck associated with the migration out of Africa and the peopling of the world that many populations have, but not all. Based on genetic data the timing is between 100-50Kya, with a lot of the uncertainty coming from converting generation times to years (i.e. how many years on average between parents and offspring). This is a nice reference: https://sci-hub.se/https://www.nature.com/articles/nature213...