The picture says "enamel-mimicking" and the text says "protective coating that mimics the structure and function of natural enamel", so it looks like a protective layer, not true repair. I've been using a paste with novamin lately, it also creates a protective layer and is also marketed as "repair". I like it and feel some heat when it contacts with teeth, so the chemical reaction must be working. But the marketing leaves a bad taste in the mouth.
I don't know what this new hairpaste does, but Novamin promotes re-enamelization of teeth, which is where mineral ions like calcium bond themselves to the tooth and fill in small pits and fissures. It's not regrowing actual enamel, it's probably not going to fill in any pits you can see with the naked eye, but it's a real and beneficial effect. Actually any fluoride toothpaste also does this, but Novamin may be a bit more effective at it.
Conclusion
Review shows that Novamin has significantly less clinical evidence to prove its effectiveness as a remineralization agent in treating both carious and non-carious lesion. Hence, better designed clinical trials should be carried out in the future before definitive recommendations can be made.
Was thinking about oddities of language recently (happens a lot since moving to Germany), specifically how "toothpaste" isn't made from teeth and "tomato paste" isn't something you rub onto a tomato.
So anyway, should we be calling this "hairpaste for teeth", or "toothpaste from hair"?
This semantic variability in the relation between the two nouns of a compound is pretty common in compound nouns: "Y made of X", like "tomato paste", "Y used (somehow) for X" (like "toothpaste", "paintbrush", "electrical outlet"--here an adjective, but still a lexicalized phrase), "Y in X" ("treehouse"), "Y for X" ("doghouse"), "Y containing X" ("paint can"), not to mention metaphorical uses, with some etymological relation between X and Y ("moon shot", "crapshoot", "greenhouse"), and so on. Not to mention multi-word compounds, like "greenhouse gas"--but I'm sure you've seen lots of those in Germany :).
“Toothpaste” is the commonly accepted English word (in most English dialects, as far as I’m aware) for that paste which we use to clean our teeth with a brush. So I expect we’ll call it “toothpaste” regardless of the exact chemical composition.
If keratin is the active ingredient, I would suspect the exact source doesn’t really matter.
Sensodyne toothpaste has two lines: one that contains a mild painkiller (Rapid Relief) and one that [claims to] repair small cracks in teeth (Repair & Protect).
I use the latter. I do not know if it works, but I use it. I have never suffered from tooth pain before or after.
That’s very good news, but we’ll have to wait a little bit:
>>> “keratin-based enamel regeneration could be made available to the public within the next two to three years.”
nHA is prohibitively expensive to produce and the most effective process that produces the smallest particles is patent-protected by Sangi, and therefore many nHA toothpaste brands only contain a fraction of the concentration used to produce the effective results reported in academic studies (1-2% instead of 10%).
If keratin toothpastes can be produced more economically they could be a better option for mass adoption. For anyone who wants to try nHA toothpaste for remineralization, I can only recommend Sangi Apagard Royal toothpaste ($$$) but it does work quite well when used as directed.
I wonder if this will fall into 'supplement' territory for US approval in toothpaste. I can imagine there would be a lot of manufacturers throwing it in without testing to see if their formulation actually works or not.
Any fluoride paste quietly calcificates your pineal gland. Try something natural, like Xylitol or even just pour a tea spoon of sodium bicarbonate into a glass of water and wash your teeth with it. Keep the mix in your mouth for 5 minutes. You can also use sunflower oil (a spoon of it) and rinse it in your mouth for 15-20 minutes.
* As far as I understood, calcium needs a scaffold to attach to bones and teeth - collagen, as in gelatine, can seemingly support the regeneration of the gums, as well as some limited regeneration of the teeth
* Personal Note: I used to have knee pain in my twenties when I still ate a standard diet, when I took collagen it took about a month until the knee pain went away
* Teaspoon in the morning was enough
* Overdosing on Collagen might create some problems - might wanna read up on this
>Unlike bones and hair, enamel does not regenerate, once it is lost, it’s gone forever.
This simply isn't true. I've chipped two teeth at separate times. Both healed up over the years. I still have all my teeth, including wisdom teeth. No dental work in my lifetime.
“The root of the problem” is a more usual usage, but is just as readily applied (ha get it) as “the root of the solution”, especially when a dental pun can be bonded (puns are swell) to the headline (I can’t think of a way to pun on gumline here).
I found the phrasing really difficult to read and understand, even though I got the pun, so you’re not alone in that.
I recently started using a nano-hydroxyapatite based toothpaste. It can't restore enamel but does better at remineralization than fluoride, hopefully it will be a good intermediate for me until something regenerative is available.
It seems to me the two are effectively the same unless you have significantly misshaped teeth (remineralizing vs regenerating). I also use hydroxyapatite, just to reduce my fluoride exposure, although I believe fluoride is supposed to be a more potent remineralizer (and fluorapatite is allegedly stronger than natural hydroxyapatite). But the upside is that I don't mind swishing hydroxyapatite around in my mouth for 10 minutes, twice a day, so whenever I go to the dentist, I'm the healthiest mouth of the day (not the case pre-hydroxyapatite tooth paste/powder).
To everyone reading this you should still use flouride! Flouride and nanohydroxyapetite together both strengthen the outside layer of your teeth while strengthening the inside of them. Either alone is good, both together are great.
Hydroxyapatite based paste is incredible, and has astonished a few of my incredulous friends dealing with dental problems.
It always seemed very interesting in a cynical way that Sensodyne Repair and Protect has a European version with hydroxyapatite but doesn't offer it in the US. The only reputable US brand I'm aware of is Dr Collins Biomin, which is excellent but weak on the hydroxyapatite.
I'll be abused for it here, but I'm intractably convinced the ADA and generally despicable US health industry prefer to avoid it due to its efficacy and how much revenue would be lost if it were more common. Say what you will against this, and I'll remain convinced.
If you have no issues like sensitivity or cavities, imo I don't think there's a need to spend time optimizing the type of toothpaste. Went down that rabbit hole once reading research papers of tested and optimum fluoride concentration for remineralization, no idea why I did that considering I just use the toothpaste my partner gets and I haven't had a cavity in a decade probably
Think about it, the human genome already contains genetic encoding of keratin, it wouldn't have to evolve (incrementally bruteforce) a full protein code to "protect and repair" damaged teeth. It would just need to "happen onto" accidentally expressing it somewhere in the mouth: perhaps the mucous membrane lining the inside cheeks, perhaps the tongue, perhaps some glands in the mouth. Accidentally expressing a gene in a cell type that didn't before is much easier to occur (i.e. more likely) than generating a new functional protein: all it takes is a change in the binding site (or promoter region) so that the relevant cell type (say lining the mouth) would express it, conditionally or unconditionally.
If this were effective, our bodies would probably be doing it already.
Just to clarify: even if 2 people had the exact same genetic coding for proteins, but different coding of promoter regions, then these will have different binding affinities, modulating when proteins will or wont be expressed and at what rate. So when considering a population's genome statistics, there is already a spectrum of promotor region codes in the population, if this keratin presence on teeth had significant advantage, selection pressure would already have increased that level towards optimum.
The only caveat for my reasoning would be if it were discovered that this is exactly what happens in a healthy mouth, and that we recently discovered that conventional toothpastes have been stripping such layer of keratin by abrasion.
> If this were effective, our bodies would probably be doing it already.
Naaah, this is not how evolution works. Tooth decay was not as big of a problem for our ancestors than it is for us (more sugar and acidic soft drinks) and tooth decay becomes more of a problem for older people that already reproduced making good teeth above a certain age uninteresting from an evolutionary standpoint. (And mayebe instead of better teeth we learnded to feed grandparents soft porridge to keep them around longer for babysitting duties ;-) (see the usefulness of aunts in elephants). Just because you like to keep your teeth, doesn‘t mean that nature cares.
[+] [-] buybackoff|7 months ago|reply
[+] [-] safety1st|7 months ago|reply
[+] [-] alyx|7 months ago|reply
https://pmc.ncbi.nlm.nih.gov/articles/PMC7068624/
Conclusion Review shows that Novamin has significantly less clinical evidence to prove its effectiveness as a remineralization agent in treating both carious and non-carious lesion. Hence, better designed clinical trials should be carried out in the future before definitive recommendations can be made.
[+] [-] majkinetor|7 months ago|reply
Have you noticed something more promising ? I am not sure, because I typically do not eat carbs.
[+] [-] amelius|7 months ago|reply
I dunno, but I also feel some heat when I chew on cinnamon.
[+] [-] jbjbjbjb|7 months ago|reply
[+] [-] petulla|7 months ago|reply
[+] [-] upghost|7 months ago|reply
Hard to brush that one off!
[that was brilliant, you missed your calling. I am completely enamled :D]
[+] [-] ben_w|7 months ago|reply
So anyway, should we be calling this "hairpaste for teeth", or "toothpaste from hair"?
[+] [-] mcswell|7 months ago|reply
[+] [-] nkrisc|7 months ago|reply
If keratin is the active ingredient, I would suspect the exact source doesn’t really matter.
[+] [-] BobbyTables2|7 months ago|reply
We expect olive oil to be made from real olives, but not baby oil…
[+] [-] tacker2000|7 months ago|reply
[+] [-] readthenotes1|7 months ago|reply
[+] [-] boothby|7 months ago|reply
[+] [-] SweetSoftPillow|7 months ago|reply
[+] [-] glial|7 months ago|reply
[+] [-] tchalla|7 months ago|reply
[+] [-] bobajeff|7 months ago|reply
That's really great I hope to use this some day.
[+] [-] dotancohen|7 months ago|reply
I use the latter. I do not know if it works, but I use it. I have never suffered from tooth pain before or after.
[+] [-] sohkamyung|7 months ago|reply
[+] [-] NKosmatos|7 months ago|reply
[+] [-] HPsquared|7 months ago|reply
[+] [-] CGMthrowaway|7 months ago|reply
[+] [-] skylissue|7 months ago|reply
If keratin toothpastes can be produced more economically they could be a better option for mass adoption. For anyone who wants to try nHA toothpaste for remineralization, I can only recommend Sangi Apagard Royal toothpaste ($$$) but it does work quite well when used as directed.
[+] [-] jmward01|7 months ago|reply
[+] [-] orliesaurus|7 months ago|reply
[+] [-] tmcdos|7 months ago|reply
[+] [-] aszantu|7 months ago|reply
Gums and Collagen - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7570157/
* As far as I understood, calcium needs a scaffold to attach to bones and teeth - collagen, as in gelatine, can seemingly support the regeneration of the gums, as well as some limited regeneration of the teeth
* Personal Note: I used to have knee pain in my twenties when I still ate a standard diet, when I took collagen it took about a month until the knee pain went away
* Teaspoon in the morning was enough
* Overdosing on Collagen might create some problems - might wanna read up on this
[+] [-] panny|7 months ago|reply
This simply isn't true. I've chipped two teeth at separate times. Both healed up over the years. I still have all my teeth, including wisdom teeth. No dental work in my lifetime.
[+] [-] vhodges|7 months ago|reply
[+] [-] altairprime|7 months ago|reply
I found the phrasing really difficult to read and understand, even though I got the pun, so you’re not alone in that.
[+] [-] brnaftr361|7 months ago|reply
[+] [-] __alexs|7 months ago|reply
[+] [-] iaw|7 months ago|reply
[+] [-] lend000|7 months ago|reply
[+] [-] chucky_z|7 months ago|reply
[+] [-] eth0up|7 months ago|reply
It always seemed very interesting in a cynical way that Sensodyne Repair and Protect has a European version with hydroxyapatite but doesn't offer it in the US. The only reputable US brand I'm aware of is Dr Collins Biomin, which is excellent but weak on the hydroxyapatite.
I'll be abused for it here, but I'm intractably convinced the ADA and generally despicable US health industry prefer to avoid it due to its efficacy and how much revenue would be lost if it were more common. Say what you will against this, and I'll remain convinced.
[+] [-] unknown|7 months ago|reply
[deleted]
[+] [-] ClassicJesus|7 months ago|reply
EU citizen here.
[+] [-] Rastonbury|7 months ago|reply
[+] [-] haltcatchfire|7 months ago|reply
[+] [-] ozgrakkurt|7 months ago|reply
[+] [-] DoctorOetker|7 months ago|reply
If this were effective, our bodies would probably be doing it already.
Just to clarify: even if 2 people had the exact same genetic coding for proteins, but different coding of promoter regions, then these will have different binding affinities, modulating when proteins will or wont be expressed and at what rate. So when considering a population's genome statistics, there is already a spectrum of promotor region codes in the population, if this keratin presence on teeth had significant advantage, selection pressure would already have increased that level towards optimum.
The only caveat for my reasoning would be if it were discovered that this is exactly what happens in a healthy mouth, and that we recently discovered that conventional toothpastes have been stripping such layer of keratin by abrasion.
[+] [-] mmkhd|7 months ago|reply
Naaah, this is not how evolution works. Tooth decay was not as big of a problem for our ancestors than it is for us (more sugar and acidic soft drinks) and tooth decay becomes more of a problem for older people that already reproduced making good teeth above a certain age uninteresting from an evolutionary standpoint. (And mayebe instead of better teeth we learnded to feed grandparents soft porridge to keep them around longer for babysitting duties ;-) (see the usefulness of aunts in elephants). Just because you like to keep your teeth, doesn‘t mean that nature cares.
[+] [-] rsync|7 months ago|reply
Is this mechanism different?
[+] [-] fbn79|7 months ago|reply
[+] [-] sMarsIntruder|7 months ago|reply
[+] [-] Hnrobert42|7 months ago|reply
Hey Siri, remind me in three years to look for keratin based toothpaste.
[+] [-] satellite2|7 months ago|reply
I wonder how they got the idea to put some in it