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iaw | 6 months ago

I recently started using a nano-hydroxyapatite based toothpaste. It can't restore enamel but does better at remineralization than fluoride, hopefully it will be a good intermediate for me until something regenerative is available.

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lend000|6 months ago

It seems to me the two are effectively the same unless you have significantly misshaped teeth (remineralizing vs regenerating). I also use hydroxyapatite, just to reduce my fluoride exposure, although I believe fluoride is supposed to be a more potent remineralizer (and fluorapatite is allegedly stronger than natural hydroxyapatite). But the upside is that I don't mind swishing hydroxyapatite around in my mouth for 10 minutes, twice a day, so whenever I go to the dentist, I'm the healthiest mouth of the day (not the case pre-hydroxyapatite tooth paste/powder).

gamblor956|6 months ago

NHAP particles are smaller than fluoride particles, so they're able to penetrate farther into the porous surface of the teeth; flouride basically can only coat the surface. There is some research indicating that NHAP is more effective than flouride at remineralizing (e.g. https://pmc.ncbi.nlm.nih.gov/articles/PMC4252862/) but that flouride is more protective than NHAP because NHAP isn't protective at all. (The flouride creates a temporary sacrificial enamel-like shell layer that closes off pores in the surface of the teeth in addition to buffering acids; the NHAP will just create new enamel.)

My dentist says that NHAP is great if you have lots of cavities or drink lots of acidic drinks like soda, but once your enamel is repaired too much of NHAP can actually cause weird growths.

Dave's toothpaste has both NHAP and flouride (and the sensitivity agent used in Sensyodyne) if you're looking for the best of all worlds in the U.S.

BenjiWiebe|6 months ago

What product(s) do you recommend? I'm in the US.

chucky_z|6 months ago

To everyone reading this you should still use flouride! Flouride and nanohydroxyapetite together both strengthen the outside layer of your teeth while strengthening the inside of them. Either alone is good, both together are great.

iaw|6 months ago

Oh! To clarify. I use fluoride in the morning and hydroxyapatite at night.

eth0up|6 months ago

Hydroxyapatite based paste is incredible, and has astonished a few of my incredulous friends dealing with dental problems.

It always seemed very interesting in a cynical way that Sensodyne Repair and Protect has a European version with hydroxyapatite but doesn't offer it in the US. The only reputable US brand I'm aware of is Dr Collins Biomin, which is excellent but weak on the hydroxyapatite.

I'll be abused for it here, but I'm intractably convinced the ADA and generally despicable US health industry prefer to avoid it due to its efficacy and how much revenue would be lost if it were more common. Say what you will against this, and I'll remain convinced.

pimlottc|6 months ago

AFAIK the European version of Sensadyne Repair and Protrct uses Novamin, not Hydroxyapatite. From what I can tell, they are similar but separate chemicals.

While not sold directly in the US, Sensadyne with Novamin is available from Amazon (usually from India).

ungreased0675|6 months ago

I pick up a couple tubes of that Sensodyne every time I’m in Europe.

BenjiWiebe|6 months ago

What product(s) do you recommend? I'm in the US.