[caspper69]

LINQ? Just throwing it out there; obviously not everybody can or wants to run a C#/.NET stack, but entity framework (core) is about as close as you can get to the perl and regex integration. I think Ruby on Rails gets there too, but I'm not a RoR guy, so I can't comment.

[wredcoll]

I think linq is the closest anyone has come so far, although it is a dsl with slightly different semantics as I understand.

ActiveRecord, RoR's ORM is the complete opposite.