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Using acetaminophen during pregnancy may increase childrens autism and ADHD risk

57 points| spchampion2 | 6 months ago |hsph.harvard.edu

15 comments

order

caminante|6 months ago

Ibuprofen is the big "no no" for pregnant women past first trimester.

Meanwhile, this is like a 'press release centipede' of AI summary links.

apparent|6 months ago

Where I live, tylenol is generally seen as less effective and less risky than aspirin or advil. I wonder how many pregnant mothers have taken it in a misguided attempt to reduce the risk of side effects.

brendoelfrendo|6 months ago

Acetaminophen is often recommended for pregnant women because NSAIDs carry risks in pregnancy that have been known for far longer. Indeed, the researchers here indicate that they recommend judicious use, not "broad limitation" because failing to manage fevers during pregnancy also carries risk. So there is no good option, only an understanding that all the options carry drawbacks and that we should go into maternal healthcare with our eyes open.

semicognitive|6 months ago

Overly decreasing inflammation in fetal brains causes over connection of neurons and leads to autism / adhd / schizophrenia?

flatline|6 months ago

Acetaminophen is not an anti-inflammatory.

Mistletoe|6 months ago

Oh good, we haven’t been taking that by the kilo since 1955.

uncircle|6 months ago

I always wondered if in the US people take pills by the handful as they are commonly portrayed in movies and TV. I am pretty sure I have seen represented a person with an heachache fill their palm with 10 pills of clearly marked Tylenol bottles, and somehow always gulp them down with no water.

To this day I wonder if it’s artistic choice or that’s how people take pills over there. Would explain a few things.

tomhow|6 months ago

Earlier post from today of a different study about the effects of paracetamol/acetaminophen on foetal development:

Paracetamol disrupts early embryogenesis by cell cycle inhibition - https://news.ycombinator.com/item?id=45006296 - Aug 2025 (167 comments)

brendoelfrendo|6 months ago

I don't think this is a dupe of the linked post? This is a meta-analysis of several studies, while that other link goes to a specific study that happened to release a few days later.