[neltnerb]

I wonder if enough of them exist to even do a study like that.

I have encountered side effects that probably no one has seen before, simply because of rarity and peculiarity of behavior. You don't run into a ton of people using both interferon and doing karate, so if bruising more easily happens 10% of the time... would anyone notice?

Personally I would be more worried about persistent inflammation causing inflammatory disorders, of which there are many. If there are like 10,000 individuals with this trait then there just aren't enough to detect. But that seems direct... wouldn't you expect something like this to potentially even destroy viral reservoirs over time?

The fact that this is short term in the treatment made me 1000x more comfortable with the idea in any case.

[anjel]

I wonder if large numbers of humans acquire this mutation, how viruses would adapt to this evolutionary pressure?

[nine_k]

They would still have too many other possible hosts.Or maybe they'd find a way to attack that very system, similarly how HIV attacks the immune system.