[matteason]

Are there any software-oriented licenses in the same spirit as CC BY-NC? I'm aware that it likely wouldn't be a true Open Source license if you completely prohibit commercial use, but I've looked for a license like that in the past and didn't have any luck

[WorldMaker]

The GPL is pretty close and still true Open Source. The GPL is technically closest to CC BY-SA, but the virality of the GPL (or especially the AGPL if you like/trust it, which I don't but that's a longer conversation) has been enforced enough that a lot of companies, especially smaller ones with fewer lawyers are wary of it/try to avoid it, but even a lot of big companies with many lawyers can be very conservative about how they use or don't use GPL software.

But yeah, both FSF and OSI see some commercial use as a freedom a Free/Open Source license should have so if you want a truly non-commercial license both will tell you it is not by definition a Free/Open Source license.