It's not totally novel, but it's very cool to see the continued simplification of protein folding models - AF2 -> AF3 was a reduction in model architecture complexity, and this is a another step in the direction of the bitter lesson.
I’m not sure AF3’s performance would hold up if it hadn’t been trained on data from AF2 which itself bakes in a lot of inductive bias like equivariance
hashta|5 months ago