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Magmalgebra | 4 months ago

While I get what you're saying I don't think this is what most people think of as "solved".

The brass tacks are:

1. Estimates for the cost of obesity globally are somewhere around 2 trillion dollars.

2. Telling people to diet and exercise usually did not get them to lose weight

3. Giving people semaglutide does get them to lose weight

So many people in my life who were unhappy and struggling with their weight are now happy because semaglutide worked where advice about diet and exercise did not. I can't imagine most rare disease drugs will have that level of impact.

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asdff|4 months ago

The advice about diet and exercise did not fail to work. What failed was listening to that advice. It works for people who listen.

And what is more you will not be healthy at 80 years old living otherwise sedentary life with ozempic keeping the weight you should be carrying off. You will have no muscle mass. You will be frail and in poor health compared to your peers who cultivated and maintained muscle mass through their life. You will not only have a weak body but your organ health will be in decline. You will have weak lungs and heart. This is going to make medical intervention at the end of your life all the more complicated. Make it difficult for you to survive from things.

Now imagine how much of the world might change if we solved the issue of "uninformed people failing to listen to expert advice." I imagine we'd meet all our climate goals and pollution goals in a generation if not less.