[Laremere]

Payload capacities to trans-lunar injection (source wikipedia):

SLS Block 1: >27,000 kg (59,500 lb)

SLS Block 1B: 42,000 kg (92,500 lb)

SlS Block 2: >46,000 kg (101,400 lb)

Vulcan Centaur: 12,100 kg (26,700 lb)

New Glenn: 7,000 kg (15,000 lb)

Orion crew module by itself weighs 10,400 kg (22,900 lb), the service module is 15,461 kg (34,085 lb).

Orion is a heavy spacecraft. SLS, like or not (I don't), it has a lot of lift. Unless you're sticking an Orion inside of a Starship (lol), Orion basically dies with SLS.

[dotnet00]

New Glenn at least claims to eventually be able to put 45,000kg to LEO. Once in orbit, refueling or docking boost stages can come into play. With Vulcan, I have mainly heard of proposals involving modifying Orion to dock the service module in orbit after separate launches.

Supposedly, as of a week ago, LM sees at least some possible routes to having Orion without SLS to not outright give up on the idea, but doesn't have specifics for now: https://arstechnica.com/space/2025/10/once-unthinkable-nasa-...