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dpeckett | 4 months ago
There's not a lot of evidence that most common sleep medications are associated with long term improvements in health outcomes. Most have substantial detrimental effects on sleep architecture, can exacerbate underlying issues like apnea etc. Interesting the gabapentanoids (chronic pain) and Xyrem (narcolepsy) are associated with increased slow wave sleep. More research is needed (eg the DORA drugs [1]).
Thankfully circadian issues (in the absence of sleep loss) aren't associated with negative health outcomes. Just a case of finding a way to modify ones life to accommodate them.
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