[richbell]

> He said that his team had hoped for it to become a prescription medicine dosed at 500 mcg, because anything higher gave paradoxical effects and actually made sleep worse.

Tangentially, I'm reminded of this interview around ~31m.

TL;DR they found something that promoted deeper sleep, but people didnt necessary feel "well rested", and so it was shelved for something that subjectively improved sleep but actually reduced the quality of sleep.

https://youtu.be/UWhk2LMDwCc?t=31m