[capyba]

Interesting… though seems to be limited to basal insulin doses. The basal/bolus paradigm using pens or pump (both injections) can’t really go away without a ‘smart’ insulin that stays in the bloodstream, inactive, and only reacts to changing glucose levels.

[lolc]

Yeah could be useful for basal delivery. But I wonder how variable it will be. Temperature, moisture, rub-off, other lotions, could all hinder the delivery. Don't want additional variability on a medication this sensitive to dosage.

The biggest danger I see that it's a deadly cream. Untrained people are unlikely to inject insulin by mistake. With a cream, they might just rub some on.

[capyba]

Honestly hadn’t even thought of that - easy to say “more is better, right?” or miscalculate what the dose should be.