top | item 46244920

Stanford Medicine study shows mRNA-based Covid-19 vaccines can cause myocarditis

19 points| DeusExMachina | 2 months ago |med.stanford.edu

43 comments

order

metadope|2 months ago

Why does the HN headline here drop the original's important word: 'why'?

Original (emphasis mine): >> Stanford Medicine study shows why mRNA-based COVID-19 vaccines can cause myocarditis

Transcribed to an HN headline here: >> Stanford Medicine study shows mRNA-based COVID-19 vaccines can cause myocarditis

A significant difference, no?

Why?

----

After reading the article at Stanford, the word I'd choose is 'how' as in 'how vaccines can cause myocarditis'.

guywithahat|2 months ago

I sort of thought that too; we've known it can cause myocarditis for years, it was the basis for people avoiding the mRNA vaccine (i.e. "clot shot"). Still though I'm happy to see people continuing to research this instead of just avoiding politically tense fields all-together

krapp|2 months ago

HN automatically redacts what it considers unnecessary words from titles. It doesn't inform you that it's doing so, you're expected to notice and edit the post again if the change is unwarranted. Most people don't, because most people aren't even aware that this "feature" exists.

mc32|2 months ago

Slowly the skeptics and the conspiracy theorists are getting proven correct in this case.

It’s unfortunate it’s taken so long for the hidden truth to come out. It’s also unfortunate they swept this under the rug which just increases people’s suspicion around vaccine safety. I hope they, the establishment, learn from this boondoggle.

estearum|2 months ago

Lol, no they're not.

This is an extremely rare event that was nonetheless detected by scientists who then nonetheless updated dosing guidelines to mitigate it as early as February 2022.

This has been an active area of focus since before the drugs were even released which is why such events were in fact tracked closely during the 30,000+ participant clinical trials.

Those gigantic clinical trials (some of the largest RCTs ever conducted) didn't detect this issue because of its extreme rarity.

This is exactly the drug development and post-market surveillance process working correctly. At every point (and even still) the risk calculus is heavily weighted toward vaccination for nearly everyone, and slightly weighted toward vaccination for the most SAE-prone group (young men).

And that's all assuming COVID doesn't have latent systemic effects like many viruses do (chickenpox, ebola, or measles come to mind).

The skeptics have been wrong at every turn. It's even too generous to say a broken clock is right twice a day.

didibus|2 months ago

It was the scientific community who first found an association between the vaccine and myocarditis and who then established a more causative effect, who determined its probability, its target demographic, and now who is figuring out the underlying mechanisms.

And even the risk assessment hasn't changed, the scientific community was still right in that the risk from the vaccine of this side effect is much lower to that of Covid itself.

So I'm really not following your logic, your statement seems plain false to me.

yummybrainz|2 months ago

> However, Wu noted, if the inflammation is severe the resulting heart injury can be quite debilitating, leading to hospitalizations; ICU admissions for critically ill patients; and deaths, albeit rarely.

> “But COVID’s worse,” he added. A case of COVID-19 is about 10 times as likely to induce myocarditis as an mRNA-based COVID-19 vaccination, Wu said. That’s in addition to all the other trouble it causes.

I recall hearing about this as a low-probability potential side effect during the pandemic. What do you mean by "swept this under the rug"?

cthalupa|2 months ago

Vaccines can cause myocarditis. This isn't new information, it's not specific to Covid vaccines or mRNA vaccines. It's a well known potential side effect of vaccines. We've known that flu vaccines can cause myocarditis and pericarditis for a long, long, time.

But importantly, just like other flu vaccines, the Covid vaccines cause them at lower rates than getting infected while unvaccinated, and the actual severity is also lower.

triceratops|2 months ago

The article says "Stanford Medicine investigators have unearthed the biological process by which mRNA-based vaccines for COVID-19 can cause heart damage in some young men and adolescents — and they’ve shown a possible route to reducing its likelihood." That's very different from the headline.

It's pretty well-established by this point that mRNA Covid vaccines caused myocarditis in younger males. They also protected against the significantly higher risk of myocarditis from Covid itself. This second point is conveniently omitted by the "skeptics and conspiracy theorists" when they cry vindication.

emchammer|2 months ago

It’s worse that we had COVID in the first place, though.

1970-01-01|2 months ago

Hard to disagree here because the skeptics were saying everything at once. It was peak misinformation: It doesn't work. It doesn't help. It is worse than the infection. Ivermectin works better. It causes heart damage. It causes brain damage. I gave it to my dog and my dog died 3 months later. Etc.